![SY Investing on X: "$SAGE (-62% PM) announced pivotal Ph 3 MOUNTAIN results of SAGE-217 in MDD. Study didn't meet primary endpoint. #Fail SAGE-217 showed mean reduction of 12.6 in HAM-D total SY Investing on X: "$SAGE (-62% PM) announced pivotal Ph 3 MOUNTAIN results of SAGE-217 in MDD. Study didn't meet primary endpoint. #Fail SAGE-217 showed mean reduction of 12.6 in HAM-D total](https://pbs.twimg.com/media/ELByJvbU8AAcv6j.jpg)
SY Investing on X: "$SAGE (-62% PM) announced pivotal Ph 3 MOUNTAIN results of SAGE-217 in MDD. Study didn't meet primary endpoint. #Fail SAGE-217 showed mean reduction of 12.6 in HAM-D total
![SAGE-217, A Novel GABAA Receptor Positive Allosteric Modulator: Clinical Pharmacology and Tolerability in Randomized Phase I Dose-Finding Studies | Clinical Pharmacokinetics SAGE-217, A Novel GABAA Receptor Positive Allosteric Modulator: Clinical Pharmacology and Tolerability in Randomized Phase I Dose-Finding Studies | Clinical Pharmacokinetics](https://media.springernature.com/lw685/springer-static/image/art%3A10.1007%2Fs40262-019-00801-0/MediaObjects/40262_2019_801_Fig2_HTML.png)
SAGE-217, A Novel GABAA Receptor Positive Allosteric Modulator: Clinical Pharmacology and Tolerability in Randomized Phase I Dose-Finding Studies | Clinical Pharmacokinetics
Zuranolone. GABAA receptor positive allosteric modulator, Treatment of major depressive disorder, Treatment of postpartum depres
SAGE-217 In Major Depressive Disorder: A Multi-Center, Randomized, Double-Blind, Phase 2 Placebo-Controlled Trial
![Figure 1 from Neuroactive Steroids. 2. 3α-Hydroxy-3β-methyl-21-(4-cyano-1H-pyrazol-1'-yl)-19-nor-5β-pregnan-20-one (SAGE-217): A Clinical Next Generation Neuroactive Steroid Positive Allosteric Modulator of the (γ-Aminobutyric Acid)A Receptor ... Figure 1 from Neuroactive Steroids. 2. 3α-Hydroxy-3β-methyl-21-(4-cyano-1H-pyrazol-1'-yl)-19-nor-5β-pregnan-20-one (SAGE-217): A Clinical Next Generation Neuroactive Steroid Positive Allosteric Modulator of the (γ-Aminobutyric Acid)A Receptor ...](https://d3i71xaburhd42.cloudfront.net/04e63722ff904394f500d4009d335d9ad3f36d7c/2-Figure1-1.png)